RAPGEFL1

Across TCGA cell cohorts, RAPGEFL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,038 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAPGEFL1-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription, elongation, Negative regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with RAPGEFL1 in more than 10 cancer types. Because this analysis shows association rather than direction, both RAPGEFL1-to-partner and partner-to-RAPGEFL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA-templated transcription, elongation grouped by RAPGEFL1-low versus RAPGEFL1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAPGEFL1→partner) and Y-score (partner→RAPGEFL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of DNA-templated transcription, elongation →	+0.180	+1.115	<.001	<.001	3	11
OVARY	Negative regulation of myoblast fusion →	+0.103	+1.129	<.001	<.001	3	11
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.104	+1.129	<.001	<.001	3	11
BONE	Negative regulation of mRNA processing →	+0.137	+1.398	<.001	<.001	3	11
BONE	Copper ion export →	-0.177	-1.199	.002	.002	3	11
BONE	Regulation of DNA repair →	+0.113	+1.307	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,038 associations by consensus.

Negative regulation of DNA-templated transcription, elongation by RAPGEFL1 expression — BONE

Explore this box plot interactively →