RAP2C

Across TCGA patient cohorts, RAP2C protein abundance is significantly associated with the RNA expression of many other genes, with 8,377 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RAP2C-associated genes across cancer lineages are ZFP14, GK-AS1, and FAM214B. Each is linked with RAP2C in more than 3 cancer types. Because this analysis shows association rather than direction, both RAP2C-to-partner and partner-to-RAP2C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAP2C versus ZFP14 in HNSC, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAP2C→partner) and Y-score (partner→RAP2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZFP14 →	-0.687	-0.303	<.001	<.001	3	4
UCEC	GK-AS1 →	+1.336	+0.586	<.001	<.001	3	4
OV	FAM214B →	+0.650	+0.481	<.001	<.001	3	4
OV	MPP1 →	+0.637	+0.362	.003	.003	3	4
OV	WAS →	+0.882	+0.353	.001	.005	3	4
OV	SPI1 →	+0.908	+0.356	.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,377 associations by consensus.

RAP2C vs ZFP14 — HNSC

Explore this scatter interactively →