RAP2C

Across TCGA patient cohorts, RAP2C mutation is significantly associated with the RNA expression of many other genes, with 3,598 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAP2C-associated genes across cancer lineages are RNU4-65P, RNA5SP413, and RNA5SP417. Each is linked with RAP2C in more than 1 cancer types. Because this analysis shows association rather than direction, both RAP2C-to-partner and partner-to-RAP2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-65P grouped by RAP2C-low versus RAP2C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAP2C→partner) and Y-score (partner→RAP2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU4-65P →	+0.097	+2.453	<.001	.005	3	2
UCEC	RNA5SP413 →	+0.799	+1.625	<.001	.001	3	2
UCEC	RNA5SP417 →	+0.402	+2.167	<.001	<.001	3	2
CESC	LINC02559 →	+0.749	+4.020	<.001	.009	3	2
UCEC	PPIL2 →	+0.354	+1.818	<.001	<.001	3	1
UCEC	SNRPD3 →	+0.421	+2.050	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,598 associations by consensus.

RNU4-65P by RAP2C expression — UCEC

Explore this box plot interactively →