RAP2C

Across TCGA cell cohorts, RAP2C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,452 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RAP2C-associated GO terms across cancer lineages are Establishment of endothelial intestinal barrier, Negative regulation of organelle assembly, and Regulation of ubiquitin-dependent protein catabolic process. Each is linked with RAP2C in more than 12 cancer types. Because this analysis shows association rather than direction, both RAP2C-to-partner and partner-to-RAP2C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of endothelial intestinal barrier grouped by RAP2C-low versus RAP2C-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAP2C→partner) and Y-score (partner→RAP2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Establishment of endothelial intestinal barrier →	+0.186	+1.450	<.001	<.001	3	12
BONE	Negative regulation of organelle assembly →	+0.056	+0.648	<.001	.005	3	12
BLOOD_Lymphoma	Regulation of ubiquitin-dependent protein catabolic process →	+0.041	+0.743	<.001	.002	3	11
SKIN	Regulation of gene silencing by regulatory ncRNA →	+0.116	+0.884	<.001	<.001	3	11
KIDNEY	Phosphatidylinositol biosynthetic process →	+0.050	+0.611	<.001	.002	3	11
LUNG_NSCLC_LUSC	Post-Golgi vesicle-mediated transport →	+0.073	+0.985	.002	.007	1	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,452 associations by consensus.

Establishment of endothelial intestinal barrier by RAP2C expression — BREAST

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