RAP2C-AS1

Across TCGA pan-cancer cohorts, RAP2C-AS1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated RAP2C-AS1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RAP2C-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RAP2C-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LUAD show a favorable association.

BLCA, KIRC, and LUAD are the cancer types where RAP2C-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	II,III,IV	0.636	0.782	.001	100	view →
KIRC	OS	Tertile	All	0.753	0.515	<.001	59	view →
LUAD	OS	Median	II,III,IV	0.335	0.161	.012	47	view →
THCA	OS	Quartile	II,III,IV	0.508	0.880	.002	39	view →
ESCA	OS	Tertile	All	0.762	0.564	.012	29	view →
ACC	DFS	Quartile	III,IV	0.487	0.090	.001	24	view →
MESO	OS	Median	All	0.731	0.292	.002	21	view →
LIHC	DFS	Quartile	III,IV	0.410	0.090	.004	21	view →
LUSC	DFS	Quartile	III,IV	0.077	1.000	<.001	20	view →
STAD	DFS	Median	IV	0.278	0.630	.003	18	view →
OV	DFS	Median	II,III,IV	0.124	0.192	.007	16	view →
SKCM	DFS	Median	III,IV	0.349	0.175	.005	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

RAP2C-AS1–BLCA (OS)

Open the BLCA breakdown →