RAP2A

Across TCGA pan-cancer cohorts, RAP2A Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated RAP2A data layer compared with 25 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RAP2A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RAP2A expression acts as an unfavorable survival marker.

LUAD and KIRP are the cancer types where RAP2A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.108	0.677	<.001	20	view →
KIRP	OS	Median	All	0.248	0.705	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

RAP2A–LUAD (OS)

Open the LUAD breakdown →