RAP2A

Across TCGA cell cohorts, RAP2A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,815 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RAP2A-associated GO terms across cancer lineages are Ribosomal protein import into nucleus, Regulation of microtubule cytoskeleton organization, and Phosphatidylinositol biosynthetic process. Each is linked with RAP2A in more than 14 cancer types. Because this analysis shows association rather than direction, both RAP2A-to-partner and partner-to-RAP2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal protein import into nucleus grouped by RAP2A-low versus RAP2A-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAP2A→partner) and Y-score (partner→RAP2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Ribosomal protein import into nucleus →	+0.148	+1.056	<.001	.001	3	15
LUNG_NSCLC_LUSC	Regulation of microtubule cytoskeleton organization →	+0.065	+0.983	.003	<.001	3	11
BLOOD_Leukemia	Phosphatidylinositol biosynthetic process →	+0.041	+0.810	<.001	<.001	3	11
URINARY_TRACT	Nucleotide-excision repair, DNA gap filling →	+0.098	+1.046	.002	<.001	2	10
STOMACH	Regulation of microtubule-based process →	+0.061	+1.374	<.001	.001	3	9
BREAST	Positive regulation of mitotic sister chromatid separation →	+0.137	+1.001	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,815 associations by consensus.

Ribosomal protein import into nucleus by RAP2A expression — OESOPHAGUS

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