RAP1GAP2

Across TCGA patient cohorts, RAP1GAP2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,708 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RAP1GAP2-associated genes across cancer lineages are RRM2P3, SNAI3, and SCN1B. Each is linked with RAP1GAP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both RAP1GAP2-to-partner and partner-to-RAP1GAP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAP1GAP2 versus RRM2P3 in LUAD, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAP1GAP2→partner) and Y-score (partner→RAP1GAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RRM2P3 →	-0.734	-0.360	<.001	<.001	3	4
GBM	SNAI3 →	+0.450	+0.481	.001	<.001	3	4
BRCA	SCN1B →	+0.641	+0.422	<.001	.002	3	3
BRCA	FFAR2 →	+0.975	+0.392	<.001	<.001	3	3
GBM	PLEKHG3 →	+1.021	+0.600	<.001	<.001	3	3
GBM	CPLX2 →	+2.211	+0.609	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,708 associations by consensus.

RAP1GAP2 vs RRM2P3 — LUAD

Explore this scatter interactively →