RAP1BP1

Across TCGA pan-cancer cohorts, RAP1BP1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RAP1BP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RAP1BP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RAP1BP1 is over-expressed in tumor, although a few such as UCEC and READ show the opposite, repressed pattern.

KICH, LUAD, and HNSC are the cancer types where RAP1BP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAP1BP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	II,III,IV	+0.390	<.001	10	view →
LUAD	Male	All	+0.110	.009	5	view →
HNSC	All	III,IV	+0.044	.034	3	view →
UCEC	All	All	−0.360	.001	2	view →
READ	Female	All	−0.088	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RAP1BP1–KICH

Open the KICH breakdown →