RAP1A

Across TCGA cell cohorts, RAP1A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,761 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RAP1A-associated GO terms across cancer lineages are Zinc ion import into Golgi lumen, UDP-galactose transmembrane transport, and COPII-coated vesicle cargo loading. Each is linked with RAP1A in more than 11 cancer types. Because this analysis shows association rather than direction, both RAP1A-to-partner and partner-to-RAP1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zinc ion import into Golgi lumen grouped by RAP1A-low versus RAP1A-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAP1A→partner) and Y-score (partner→RAP1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Zinc ion import into Golgi lumen →	+0.122	+0.903	<.001	.001	3	12
URINARY_TRACT	UDP-galactose transmembrane transport →	+0.137	+1.177	.004	.001	2	11
KIDNEY	COPII-coated vesicle cargo loading →	+0.124	+0.797	<.001	<.001	3	9
BONE	Collagen biosynthetic process →	+0.223	+0.851	.002	.007	3	9
OVARY	Maintenance of protein location in cell →	+0.076	+0.696	.001	.003	3	9
SOFT_TISSUE	Negative regulation of defense response to virus →	+0.074	+0.736	.004	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,761 associations by consensus.

Zinc ion import into Golgi lumen by RAP1A expression — PANCREAS

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