RANP8

Across TCGA pan-cancer cohorts, RANP8 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RANP8’s most consistent transcriptional readouts.

The strongest signal is observed in rectum adenocarcinoma (READ), where RANP8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RANP8 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

READ, BRCA, and STAD are the cancer types where RANP8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RANP8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
READ	All	All	+0.279	.010	2	view →
BRCA	All	IV	+0.235	<.001	2	view →
STAD	All	IV	+0.123	.003	2	view →
LUSC	All	II,III,IV	−0.080	.049	1	view →
HNSC	All	All	+0.033	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

RANP8–READ

Open the READ breakdown →