Across TCGA pan-cancer cohorts, RANP3 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RANP3’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where RANP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RANP3 is over-expressed in tumor, although a few such as THCA and KIRP show the opposite, repressed pattern.
STAD, LIHC, and THCA are the cancer types where RANP3 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RANP3 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.