RANGRF

Across TCGA cell cohorts, RANGRF RNA expression is significantly associated with the go_rna of many other GO terms, with 3,443 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RANGRF-associated GO terms across cancer lineages are Telomere assembly, Attachment of mitotic spindle microtubules to kinetochore, and Cajal body organization. Each is linked with RANGRF in more than 14 cancer types. Because this analysis shows association rather than direction, both RANGRF-to-partner and partner-to-RANGRF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere assembly grouped by RANGRF-low versus RANGRF-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RANGRF→partner) and Y-score (partner→RANGRF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Telomere assembly →	+0.127	+0.848	<.001	<.001	3	15
STOMACH	Attachment of mitotic spindle microtubules to kinetochore →	+0.108	+1.050	<.001	<.001	3	12
OVARY	Cajal body organization →	+0.120	+1.022	<.001	.001	3	11
URINARY_TRACT	Regulation of synaptic transmission, dopaminergic →	+0.259	+1.001	<.001	.003	3	10
BREAST	Regulation of membrane depolarization during cardiac muscle cell action potential →	+0.143	+1.364	<.001	<.001	3	10
URINARY_TRACT	Adult walking behavior →	+1.220	+1.724	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,443 associations by consensus.

Telomere assembly by RANGRF expression — LUNG_SCLC

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