RANGAP1

Across TCGA patient cohorts, RANGAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,987 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RANGAP1-associated genes across cancer lineages are TOMM22, KLF2, and NCAPG. Each is linked with RANGAP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both RANGAP1-to-partner and partner-to-RANGAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RANGAP1 versus TOMM22 in LSCC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RANGAP1→partner) and Y-score (partner→RANGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TOMM22 →	+0.497	+0.180	<.001	<.001	3	8
CCRCC	KLF2 →	-1.101	-0.185	<.001	<.001	3	8
GBM	NCAPG →	+1.239	+0.265	<.001	<.001	3	8
BRCA	NCAPH →	+0.943	+0.301	<.001	<.001	3	8
UCEC	BUB1 →	+0.964	+0.218	<.001	<.001	3	8
UCEC	DEPDC1 →	+0.792	+0.201	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,987 associations by consensus.

RANGAP1 vs TOMM22 — LSCC

Explore this scatter interactively →