RANGAP1

Across TCGA cell cohorts, RANGAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,136 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RANGAP1-associated GO terms across cancer lineages are Positive regulation of mitotic cytokinesis, Regulation of anaphase-promoting complex-dependent catabolic process, and Mitotic spindle elongation. Each is linked with RANGAP1 in more than 17 cancer types. Because this analysis shows association rather than direction, both RANGAP1-to-partner and partner-to-RANGAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cytokinesis grouped by RANGAP1-low versus RANGAP1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RANGAP1→partner) and Y-score (partner→RANGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of mitotic cytokinesis →	+0.169	+1.060	<.001	<.001	3	18
URINARY_TRACT	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.149	+1.385	.001	.001	3	17
BONE	Mitotic spindle elongation →	+0.261	+0.993	.002	<.001	3	16
PANCREAS	Chromosome condensation →	+0.163	+0.809	<.001	<.001	3	16
BONE	Mitotic spindle midzone assembly →	+0.261	+0.993	.002	<.001	3	16
URINARY_TRACT	Protein depolymerization →	+0.132	+1.288	.003	.003	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,136 associations by consensus.

Positive regulation of mitotic cytokinesis by RANGAP1 expression — PANCREAS

Explore this box plot interactively →