RANBP3L

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RANBP3L mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RANBP3L-associated genes across cancer lineages are GJA10, GFRAL, and IQCF6. Each is linked with RANBP3L in more than 1 cancer types. Because this analysis shows association rather than direction, both RANBP3L-to-partner and partner-to-RANBP3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GJA10 grouped by RANBP3L-low versus RANBP3L-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RANBP3L→partner) and Y-score (partner→RANBP3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaGJA10 →+0.037+3.705<.001.00732
BLOOD_LeukemiaGFRAL →+0.020+4.984<.001.00231
LARGE_INTESTINEIQCF6 →+0.311+4.467<.001.00431
LARGE_INTESTINECD300H →+0.033+4.415<.001.00731
LUNG_NSCLC_LUADGPR42 →+0.016+4.887<.001.00931
LUNG_NSCLC_LUADCOX4I2 →+0.095+5.228<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

GJA10 by RANBP3L expression — BLOOD_Leukemia

Box plot of GJA10 in RANBP3L-low vs RANBP3L-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration