RANBP3

Across TCGA cell cohorts, RANBP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,572 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RANBP3-associated GO terms across cancer lineages are Negative regulation of protein localization to chromatin, Positive regulation of anaphase-promoting complex-dependent catabolic process, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with RANBP3 in more than 17 cancer types. Because this analysis shows association rather than direction, both RANBP3-to-partner and partner-to-RANBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein localization to chromatin grouped by RANBP3-low versus RANBP3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RANBP3→partner) and Y-score (partner→RANBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of protein localization to chromatin →	+0.224	+1.359	<.001	<.001	3	18
STOMACH	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.129	+0.741	<.001	<.001	3	18
BREAST	Microtubule cytoskeleton organization involved in mitosis →	+0.081	+0.678	.008	.003	3	17
LUNG_NSCLC_LUSC	Regulation of protein localization to chromatin →	+0.202	+1.277	<.001	.002	3	17
BLOOD_Lymphoma	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.137	+1.015	<.001	<.001	3	16
OVARY	Spindle localization →	+0.105	+0.807	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,572 associations by consensus.

Negative regulation of protein localization to chromatin by RANBP3 expression — LUNG_NSCLC_LUSC

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