RANBP3

Across TCGA cell cohorts, RANBP3 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RANBP3-associated genes across cancer lineages are MMP27, OR6J1, and DEFA4. Each is linked with RANBP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RANBP3-to-partner and partner-to-RANBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP27 grouped by RANBP3-low versus RANBP3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RANBP3→partner) and Y-score (partner→RANBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MMP27 →	+0.015	+4.969	<.001	<.001	3	1
BLOOD_Leukemia	OR6J1 →	+0.040	+3.234	<.001	.008	3	1
LARGE_INTESTINE	DEFA4 →	+0.026	+4.022	<.001	.006	3	1
LARGE_INTESTINE	TBC1D21 →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	OR52H1 →	+0.025	+3.347	<.001	.005	3	1
LARGE_INTESTINE	BPIFA1 →	+0.129	+3.688	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

MMP27 by RANBP3 expression — BLOOD_Leukemia

Explore this box plot interactively →