RANBP2

Across TCGA cell cohorts, RANBP2 mutation is significantly associated with the RNA expression of many other genes, with 550 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RANBP2-associated genes across cancer lineages are SERPINA12, MPC1L, and SYCP1. Each is linked with RANBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RANBP2-to-partner and partner-to-RANBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERPINA12 grouped by RANBP2-low versus RANBP2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RANBP2→partner) and Y-score (partner→RANBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SERPINA12 →	+0.021	+2.668	<.001	.005	3	2
URINARY_TRACT	MPC1L →	+0.083	+5.087	<.001	.004	3	2
LUNG_NSCLC_LUAD	SYCP1 →	+0.043	+2.527	<.001	.002	3	2
BLOOD_Lymphoma	KCNA10 →	+0.006	+2.867	<.001	.009	3	2
BLOOD_Leukemia	TNFAIP3 →	+1.432	+3.351	.003	.003	3	2
BLOOD_Leukemia	GCH1 →	+1.378	+3.351	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 550 associations by consensus.

SERPINA12 by RANBP2 expression — BLOOD_Leukemia

Explore this box plot interactively →