RANBP10

Across TCGA pan-cancer cohorts, RANBP10 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of RANBP10’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RANBP10 RNA is repressed in tumor relative to normal tissue. In most cancer types RANBP10 is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.

THCA, KIRP, and COAD are the cancer types where RANBP10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RANBP10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	IV	−1.420	<.001	11	view →
KIRP	All	II,III,IV	+0.704	<.001	11	view →
COAD	Female	All	+0.583	<.001	10	view →
LUAD	All	III,IV	−0.816	<.001	8	view →
BRCA	Female	All	−0.343	<.001	6	view →
KIRC	All	All	+0.257	<.001	5	view →
STAD	Male	II,III,IV	+0.654	.019	3	view →
LIHC	Male	All	+0.502	<.001	3	view →
CHOL	All	All	+0.859	<.001	2	view →
UCEC	All	All	−0.386	.021	2	view →
HNSC	All	All	+0.216	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

RANBP10–THCA

Open the THCA breakdown →