RANBP1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RANBP1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RANBP1-associated genes across cancer lineages are Basophils, Endothelial cells, and lymphatic Endothelial cells. Each is linked with RANBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RANBP1-to-partner and partner-to-RANBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Basophils grouped by RANBP1-low versus RANBP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RANBP1→partner) and Y-score (partner→RANBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECBasophils →+0.236+3.169.011.02031
UCECEndothelial cells →-0.045-3.127.031.02011
UCEClymphatic Endothelial cells →-0.026-3.116.044.02011
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Basophils by RANBP1 expression — UCEC

Box plot of Basophils in RANBP1-low vs RANBP1-high samples in UCEC.

Explore this box plot interactively →

Exploration