Across TCGA pan-cancer cohorts, RAMP2-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RAMP2-AS1 data layer compared with 1 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RAMP2-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RAMP2-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

KIRC, HNSC, and UCS are the cancer types where RAMP2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.920	0.836	<.001	88	view →
HNSC	DFS	Median	IV	0.722	0.555	<.001	81	view →
UCS	OS	Tertile	II,III,IV	0.758	0.239	.002	78	view →
UVM	OS	Median	All	0.763	0.409	<.001	73	view →
PAAD	DFS	Tertile	All	0.615	0.321	<.001	55	view →
BRCA	OS	Quartile	III,IV	0.974	0.792	<.001	45	view →
LUAD	OS	Median	All	0.851	0.772	.002	43	view →
COAD	DFS	Tertile	All	0.606	0.762	.005	23	view →
OV	DFS	Quartile	IV	0.521	0.246	.005	16	view →
THCA	DFS	Quartile	IV	0.938	0.451	.007	10	view →
LIHC	OS	Quartile	II,III,IV	0.555	0.794	.024	10	view →
LGG	OS	Median	All	0.940	0.828	<.001	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

Exploration

Same gene, other analysis: RAMP2-AS1 tumor-vs-normal RNA expression · all RAMP2-AS1 data types