Across TCGA patient cohorts, RALYL mutation is significantly associated with the RNA expression of many other genes, with 1,562 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RALYL-associated genes across cancer lineages are FAXDC2, JMJD6, and PHF5A. Each is linked with RALYL in more than 2 cancer types. Because this analysis shows association rather than direction, both RALYL-to-partner and partner-to-RALYL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RALYL→partner) and Y-score (partner→RALYL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAXDC2 →	-0.717	-2.169	<.001	<.001	3	3
UCEC	JMJD6 →	+0.359	+3.010	<.001	<.001	3	3
UCEC	PHF5A →	+0.338	+2.233	.004	.005	3	3
UCEC	AUP1 →	+0.245	+1.925	<.001	<.001	3	3
UCEC	DPM2 →	+0.367	+2.467	<.001	<.001	3	3
UCEC	MIGA2 →	+0.295	+1.914	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,562 associations by consensus.

Exploration

RALYL survival (RNA) · tumor vs normal (RNA) · all RALYL data types