Across TCGA cell cohorts, RALYL mutation is significantly associated with the RNA expression of many other genes, with 174 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RALYL-associated genes across cancer lineages are CCDC113, CLUAP1, and CUEDC2. Each is linked with RALYL in more than 1 cancer types. Because this analysis shows association rather than direction, both RALYL-to-partner and partner-to-RALYL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RALYL→partner) and Y-score (partner→RALYL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCDC113 →	+0.896	+3.299	.001	.004	3	1
LARGE_INTESTINE	CLUAP1 →	+0.599	+3.385	.008	.004	3	1
LARGE_INTESTINE	CUEDC2 →	+0.691	+3.064	<.001	.009	3	1
LARGE_INTESTINE	ACADM →	+0.923	+3.212	<.001	.006	3	1
LARGE_INTESTINE	RWDD3 →	+0.453	+3.212	.001	.006	3	1
LARGE_INTESTINE	METTL16 →	+0.613	+3.212	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 174 associations by consensus.

Exploration

RALYL survival (RNA) · tumor vs normal (RNA) · all RALYL data types