RALGAPB

Across TCGA pan-cancer cohorts, RALGAPB mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RALGAPB data layer compared with 26 for mass-spec protein and 11 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RALGAPB mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RALGAPB expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and GBM are the cancer types where RALGAPB mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.920	.014	24	view →
PDAC	DFS	Median	All	0.456	0.215	.004	21	view →
GBM	OS	Tertile	All	0.983	0.787	<.001	16	view →
OV	DFS	Tertile	All	0.806	1.000	.041	8	view →
LSCC	OS	Tertile	III,IV	0.979	0.473	.008	7	view →
CCRCC	DFS	Tertile	III,IV	1.000	0.828	.026	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RALGAPB–COAD (DFS)

Open the COAD breakdown →