RALGAPB

Across TCGA patient cohorts, RALGAPB mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RALGAPB-associated genes across cancer lineages are ATM, ASNS, and S6_pS240_S244. Each is linked with RALGAPB in more than 3 cancer types. Because this analysis shows association rather than direction, both RALGAPB-to-partner and partner-to-RALGAPB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by RALGAPB-low versus RALGAPB-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RALGAPB→partner) and Y-score (partner→RALGAPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ATM →	-0.953	-3.169	<.001	.017	3	4
COAD	ASNS →	+0.541	+3.178	.005	.010	3	3
BLCA	S6_pS240_S244 →	+0.311	+2.459	.049	.020	3	2
UCEC	EGFR_pY1068 →	-0.166	-1.115	.013	.022	3	2
UCEC	eIF4E →	+0.173	+2.405	.002	<.001	3	2
UCEC	Ku80 →	+0.215	+1.472	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

ATM by RALGAPB expression — COAD

Explore this box plot interactively →