RALGAPB

Across TCGA cell cohorts, RALGAPB mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RALGAPB-associated genes across cancer lineages are CSN1S1, KRT71, and RIPPLY1. Each is linked with RALGAPB in more than 1 cancer types. Because this analysis shows association rather than direction, both RALGAPB-to-partner and partner-to-RALGAPB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CSN1S1 grouped by RALGAPB-low versus RALGAPB-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RALGAPB→partner) and Y-score (partner→RALGAPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CSN1S1 →	+0.083	+4.927	<.001	.001	3	1
BLOOD_Lymphoma	KRT71 →	+0.009	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	RIPPLY1 →	+0.024	+4.191	.009	.007	3	1
BLOOD_Lymphoma	NAT2 →	+0.022	+4.927	.005	.001	3	1
BLOOD_Lymphoma	OR14A16 →	+0.012	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	TSPY1 →	+0.015	+5.247	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

CSN1S1 by RALGAPB expression — BLOOD_Lymphoma

Explore this box plot interactively →