Across TCGA patient cohorts, RALGAPA2 mutation is significantly associated with the RNA expression of many other genes, with 4,935 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RALGAPA2-associated genes across cancer lineages are DNAJC8, CDKN3, and UQCRC1. Each is linked with RALGAPA2 in more than 4 cancer types. Because this analysis shows association rather than direction, both RALGAPA2-to-partner and partner-to-RALGAPA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RALGAPA2→partner) and Y-score (partner→RALGAPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DNAJC8 →	+0.369	+1.883	<.001	<.001	3	5
UCEC	CDKN3 →	+0.529	+1.558	<.001	<.001	3	4
UCEC	UQCRC1 →	+0.303	+1.466	.001	<.001	3	4
UCEC	KCTD9 →	+0.444	+1.273	<.001	.001	3	4
UCEC	BCCIP →	+0.370	+1.412	<.001	<.001	3	4
SKCM	PSMD9 →	+0.293	+2.389	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,935 associations by consensus.

Exploration

RALGAPA2 survival (RNA) · tumor vs normal (RNA) · all RALGAPA2 data types