Across TCGA patient cohorts, RALGAPA2 mutation is significantly associated with the total protein of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RALGAPA2-associated genes across cancer lineages are ASNS, Caveolin-1, and Caspase-7-cleavedD198. Each is linked with RALGAPA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RALGAPA2-to-partner and partner-to-RALGAPA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RALGAPA2→partner) and Y-score (partner→RALGAPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ASNS →	+0.564	+3.330	.002	.005	3	3
UCEC	Caveolin-1 →	-0.498	-2.321	.014	.005	3	3
COAD	Caspase-7-cleavedD198 →	+1.435	+2.178	<.001	.035	2	3
SKCM	PDCD4 →	-0.483	-2.584	.009	.011	3	2
UCEC	14-3-3_beta →	-0.062	-1.253	.027	.049	3	2
UCEC	mTOR_pS2448 →	-0.137	-2.156	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

Exploration

RALGAPA2 survival (RNA) · tumor vs normal (RNA) · all RALGAPA2 data types