Across TCGA cell cohorts, RALGAPA2 mutation is significantly associated with the RNA expression of many other genes, with 1,740 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RALGAPA2-associated genes across cancer lineages are RPAIN, NLRP4, and VPREB1. Each is linked with RALGAPA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RALGAPA2-to-partner and partner-to-RALGAPA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RALGAPA2→partner) and Y-score (partner→RALGAPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RPAIN →	+0.596	+2.364	<.001	<.001	3	3
SOFT_TISSUE	NLRP4 →	+0.124	+2.774	.007	.005	3	2
CNS	VPREB1 →	+0.239	+3.144	.003	.002	3	2
LARGE_INTESTINE	HMGXB4 →	+0.518	+2.364	.001	<.001	3	2
LARGE_INTESTINE	TRMU →	+0.576	+1.850	<.001	.006	3	2
LARGE_INTESTINE	ADNP2 →	+0.683	+1.850	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,740 associations by consensus.

Exploration

RALGAPA2 survival (RNA) · tumor vs normal (RNA) · all RALGAPA2 data types