RALGAPA1

Across TCGA cell cohorts, RALGAPA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,743 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RALGAPA1-associated GO terms across cancer lineages are Vesicle tethering, Vesicle targeting, and Positive regulation of double-strand break repair. Each is linked with RALGAPA1 in more than 16 cancer types. Because this analysis shows association rather than direction, both RALGAPA1-to-partner and partner-to-RALGAPA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle tethering grouped by RALGAPA1-low versus RALGAPA1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RALGAPA1→partner) and Y-score (partner→RALGAPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Vesicle tethering →	+0.101	+1.167	<.001	.001	3	17
OESOPHAGUS	Vesicle targeting →	+0.099	+1.120	.001	.001	3	15
LARGE_INTESTINE	Positive regulation of double-strand break repair →	+0.064	+0.813	<.001	<.001	3	15
BLOOD_Leukemia	Copper ion export →	-0.219	-0.629	<.001	<.001	3	15
KIDNEY	Golgi organization →	+0.054	+0.816	<.001	.001	3	15
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.057	+0.775	<.001	.001	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,743 associations by consensus.

Vesicle tethering by RALGAPA1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →