RALBP1

Across TCGA pan-cancer cohorts, RALBP1 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated RALBP1 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RALBP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RALBP1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

HNSC, LSCC, and GBM are the cancer types where RALBP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	II,III,IV	0.723	0.417	.003	26	view →
LSCC	DFS	Median	II,III,IV	1.000	0.837	.005	17	view →
GBM	DFS	Median	All	0.486	0.262	.001	16	view →
CCRCC	OS	Median	II,III,IV	1.000	0.373	.006	15	view →
OV	DFS	Quartile	All	0.683	0.978	.033	8	view →
UCEC	OS	Quartile	All	1.000	0.813	.022	8	view →
LUAD	DFS	Tertile	III,IV	0.356	0.862	.035	3	view →
PDAC	OS	Tertile	III,IV	0.411	0.802	.042	2	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

RALBP1–HNSC (DFS)

Open the HNSC breakdown →