RALBP1

Across TCGA patient cohorts, RALBP1 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RALBP1-associated genes across cancer lineages are INPP4B, MEK1, and NF2. Each is linked with RALBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RALBP1-to-partner and partner-to-RALBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by RALBP1-low versus RALBP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RALBP1→partner) and Y-score (partner→RALBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.267	-2.000	.024	.029	3	2
UCEC	MEK1 →	+0.466	+2.247	<.001	.001	3	2
UCEC	NF2 →	+0.216	+1.874	.006	.049	3	2
UCEC	Shc_pY317 →	-0.178	-1.847	.001	.008	3	2
UCEC	ASNS →	+0.527	+1.847	<.001	.008	3	2
UCEC	Chk2_pT68 →	-0.143	-3.143	.036	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

INPP4B by RALBP1 expression — UCEC

Explore this box plot interactively →