RALB

Across TCGA patient cohorts, RALB mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RALB-associated genes across cancer lineages are MEK1, Tuberin_pT1462, and ATM. Each is linked with RALB in more than 1 cancer types. Because this analysis shows association rather than direction, both RALB-to-partner and partner-to-RALB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by RALB-low versus RALB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RALB→partner) and Y-score (partner→RALB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.443	+2.700	.007	.006	3	2
UCEC	Tuberin_pT1462 →	+0.302	+1.884	.003	.030	3	2
UCEC	ATM →	-0.563	-2.700	.005	.006	3	2
UCEC	14-3-3_beta →	-0.116	-1.986	.010	.032	3	1
UCEC	EGFR_pY1068 →	-0.344	-2.700	.002	.006	3	1
UCEC	ERK2 →	+0.229	+2.000	.008	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

MEK1 by RALB expression — UCEC

Explore this box plot interactively →