RAI2

Across TCGA cell cohorts, RAI2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,441 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RAI2-associated GO terms across cancer lineages are Aerobic respiration, Regulation of proteasomal protein catabolic process, and Calcium ion transport. Each is linked with RAI2 in more than 10 cancer types. Because this analysis shows association rather than direction, both RAI2-to-partner and partner-to-RAI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by RAI2-low versus RAI2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAI2→partner) and Y-score (partner→RAI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Aerobic respiration →	+0.088	+1.433	<.001	.002	3	11
STOMACH	Regulation of proteasomal protein catabolic process →	+0.076	+0.332	<.001	.003	2	11
UPPER_AERODIGESTIVE_TRACT	Calcium ion transport →	-0.061	-0.314	<.001	.005	3	10
OVARY	ATP synthesis coupled electron transport →	+0.071	+1.302	.009	.004	2	11
OVARY	Mitochondrial ATP synthesis coupled electron transport →	+0.071	+1.302	.009	.004	2	11
OVARY	Adenylate cyclase-activating G protein-coupled receptor signaling pathway →	-0.067	-2.209	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,441 associations by consensus.

Aerobic respiration by RAI2 expression — LUNG_SCLC

Explore this box plot interactively →