RAI14

Across TCGA pan-cancer cohorts, RAI14 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated RAI14 data layer compared with 26 for mass-spec protein and 12 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher RAI14 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RAI14 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

LSCC, UCEC, and HNSC are the cancer types where RAI14 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	All	0.405	0.911	.002	18	view →
UCEC	OS	Tertile	III,IV	0.502	1.000	.033	12	view →
HNSC	OS	Tertile	IV	0.631	0.939	.007	12	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	9	view →
CCRCC	OS	Quartile	All	1.000	0.782	.006	5	view →
LUAD	DFS	Median	III,IV	0.432	0.925	.047	3	view →
GBM	DFS	Median	All	0.471	0.266	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RAI14–LSCC (DFS)

Open the LSCC breakdown →