RAI1

Across TCGA cell cohorts, RAI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,713 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAI1-associated GO terms across cancer lineages are mRNA transport, Regulation of translation at synapse, modulating synaptic transmission, and Promoter clearance during DNA-templated transcription. Each is linked with RAI1 in more than 15 cancer types. Because this analysis shows association rather than direction, both RAI1-to-partner and partner-to-RAI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA transport grouped by RAI1-low versus RAI1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAI1→partner) and Y-score (partner→RAI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	mRNA transport →	+0.113	+1.185	.001	<.001	3	16
STOMACH	Regulation of translation at synapse, modulating synaptic transmission →	+0.134	+0.800	<.001	.002	3	15
UPPER_AERODIGESTIVE_TRACT	Promoter clearance during DNA-templated transcription →	+0.115	+1.107	.006	.003	3	15
UPPER_AERODIGESTIVE_TRACT	RNA polymerase II promoter clearance →	+0.115	+1.107	.006	.003	3	15
BREAST	Regulation of mRNA processing →	+0.074	+0.872	<.001	.004	3	15
UPPER_AERODIGESTIVE_TRACT	mRNA export from nucleus →	+0.109	+1.101	.003	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,713 associations by consensus.

mRNA transport by RAI1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →