RAF1

Across TCGA patient cohorts, RAF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,435 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RAF1-associated proteins across cancer lineages are TOP2B, ANKRD28, and COPG1. Each is linked with RAF1 in more than 6 cancer types. Because this analysis shows association rather than direction, both RAF1-to-partner and partner-to-RAF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAF1 versus TOP2B in GBM, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RAF1→partner) and Y-score (partner→RAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TOP2B →	+0.535	+0.409	<.001	<.001	3	7
LSCC	ANKRD28 →	+0.228	+0.344	.003	.001	3	5
GBM	COPG1 →	-0.272	-0.311	<.001	<.001	3	5
GBM	RBSN →	+0.190	+0.218	<.001	<.001	3	4
GBM	SETMAR →	+0.394	+0.353	<.001	<.001	3	4
LUAD	DCAF1 →	+0.293	+0.319	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,435 associations by consensus.

RAF1 vs TOP2B — GBM

Explore this scatter interactively →