RAF1

Across TCGA cell cohorts, RAF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,338 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAF1-associated GO terms across cancer lineages are P-body assembly, Regulation of chromosome condensation, and Protein localization to chromosome. Each is linked with RAF1 in more than 17 cancer types. Because this analysis shows association rather than direction, both RAF1-to-partner and partner-to-RAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, P-body assembly grouped by RAF1-low versus RAF1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAF1→partner) and Y-score (partner→RAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	P-body assembly →	+0.117	+0.940	<.001	<.001	3	18
BONE	Regulation of chromosome condensation →	+0.210	+0.647	<.001	<.001	3	17
BREAST	Protein localization to chromosome →	+0.084	+0.860	<.001	.001	3	17
SOFT_TISSUE	Negative regulation of chromosome condensation →	+0.147	+0.783	<.001	<.001	3	16
SOFT_TISSUE	Regulation of double-strand break repair via homologous recombination →	+0.087	+1.007	.001	<.001	3	16
SOFT_TISSUE	Regulation of double-strand break repair →	+0.077	+1.026	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,338 associations by consensus.

P-body assembly by RAF1 expression — LARGE_INTESTINE

Explore this box plot interactively →