Across TCGA patient cohorts, RAET1K mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RAET1K-associated genes across cancer lineages are PDCD4, p53, and Shc_pY317. Each is linked with RAET1K in more than 1 cancer types. Because this analysis shows association rather than direction, both RAET1K-to-partner and partner-to-RAET1K results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAET1K→partner) and Y-score (partner→RAET1K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.747	-3.160	.002	.019	3	1
SKCM	p53 →	+0.313	+2.824	.006	.036	2	1
SKCM	Shc_pY317 →	+0.300	+2.824	.009	.036	2	1
UCEC	MEK1 →	+0.454	+3.321	.017	.010	2	1
SKCM	CD49b →	+0.419	+2.824	.003	.036	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

RAET1K survival (RNA) · tumor vs normal (RNA) · all RAET1K data types