RAE1

Across TCGA patient cohorts, RAE1 mutation is significantly associated with the RNA expression of many other genes, with 3,336 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAE1-associated genes across cancer lineages are RPS29P26, TRGJP2, and SNORA84. Each is linked with RAE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAE1-to-partner and partner-to-RAE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS29P26 grouped by RAE1-low versus RAE1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAE1→partner) and Y-score (partner→RAE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPS29P26 →	+0.348	+7.930	<.001	.008	3	2
UCEC	TRGJP2 →	+0.356	+1.704	<.001	.001	3	2
UCEC	SNORA84 →	+0.444	+1.642	.001	<.001	3	2
UCEC	TRBV21-1 →	+0.258	+1.824	<.001	<.001	3	2
SKCM	RN7SL575P →	+0.092	+3.302	.001	.009	3	1
UCEC	MTCO1P40 →	-0.964	-1.796	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,336 associations by consensus.

RPS29P26 by RAE1 expression — LUAD

Explore this box plot interactively →