RAE1

Across TCGA cell cohorts, RAE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,762 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAE1-associated GO terms across cancer lineages are DNA-templated transcription initiation, Transcription preinitiation complex assembly, and DNA replication initiation. Each is linked with RAE1 in more than 15 cancer types. Because this analysis shows association rather than direction, both RAE1-to-partner and partner-to-RAE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by RAE1-low versus RAE1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAE1→partner) and Y-score (partner→RAE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated transcription initiation →	+0.095	+0.741	<.001	<.001	3	16
BONE	Transcription preinitiation complex assembly →	+0.088	+0.690	<.001	.001	3	14
BONE	DNA replication initiation →	+0.259	+0.871	<.001	<.001	3	14
BONE	Pyrimidine nucleoside monophosphate biosynthetic process →	+0.122	+0.597	.009	.003	3	14
BONE	Sister chromatid cohesion →	+0.119	+0.657	.001	.002	3	13
BONE	Regulation of DNA repair →	+0.087	+0.609	<.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,762 associations by consensus.

DNA-templated transcription initiation by RAE1 expression — BONE

Explore this box plot interactively →