RAE1

Across TCGA cell cohorts, RAE1 mutation is significantly associated with the drug of many other genes, with 19 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RAE1-associated genes across cancer lineages are Mirin, 5-Fluorouracil, and Niraparib. Each is linked with RAE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAE1-to-partner and partner-to-RAE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mirin grouped by RAE1-low versus RAE1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAE1→partner) and Y-score (partner→RAE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Mirin →	+0.471	+2.646	.012	.047	3	1
LARGE_INTESTINE	5-Fluorouracil →	+0.619	+2.769	.033	.040	3	1
LARGE_INTESTINE	Niraparib →	+0.358	+2.646	.045	.047	3	1
LARGE_INTESTINE	LMP744 →	+0.788	+2.649	.019	.046	3	1
LARGE_INTESTINE	kb NB 142-70 →	+0.576	+2.652	.013	.045	3	1
LARGE_INTESTINE	ETP-45835 →	+0.273	+2.652	.023	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Mirin by RAE1 expression — LARGE_INTESTINE

Explore this box plot interactively →