RADX

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RADX protein abundance is significantly associated with the protein abundance of many other proteins, with 3,062 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RADX-associated proteins across cancer lineages are FES_S440, PIPOX, and IGHV3-11. Each is linked with RADX in more than 1 cancer types. Because this analysis shows association rather than direction, both RADX-to-partner and partner-to-RADX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RADX versus FES_S440 in CCRCC, with a Pearson correlation of -0.55.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RADX→partner) and Y-score (partner→RADX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCFES_S440 →-0.654-0.879<.001<.00132
LSCCPIPOX →+0.993+1.073.002.00132
GBMIGHV3-11 →+1.069+1.386.004<.00132
GBMSHFL →-0.308-0.543<.001<.00132
BRCARPL18A_T24 →-0.932-1.818<.001<.00132
CCRCCMYO9A_S1299 →+0.288+0.480<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,062 associations by consensus.

RADX vs FES_S440 — CCRCC

Per-sample scatter of RADX vs FES_S440 in CCRCC (Pearson r = -0.55).

Explore this scatter interactively →

Exploration