RADIL

Across TCGA patient cohorts, RADIL mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RADIL-associated genes across cancer lineages are PCNA, TFRC, and eEF2. Each is linked with RADIL in more than 2 cancer types. Because this analysis shows association rather than direction, both RADIL-to-partner and partner-to-RADIL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by RADIL-low versus RADIL-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RADIL→partner) and Y-score (partner→RADIL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PCNA →	+0.197	+1.887	.043	.029	3	3
COAD	TFRC →	+0.568	+2.141	.006	.010	3	3
COAD	eEF2 →	+0.327	+1.593	.004	.043	3	2
UCEC	eIF4E →	+0.241	+2.247	.001	.001	3	2
COAD	ERCC1 →	+0.138	+1.593	.041	.043	3	1
COAD	ETS-1 →	+0.216	+1.610	.020	.042	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

PCNA by RADIL expression — COAD

Explore this box plot interactively →