RADIL

Across TCGA cell cohorts, RADIL mutation is significantly associated with the RNA expression of many other genes, with 555 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RADIL-associated genes across cancer lineages are DKKL1, OR1C1, and SSMEM1. Each is linked with RADIL in more than 1 cancer types. Because this analysis shows association rather than direction, both RADIL-to-partner and partner-to-RADIL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DKKL1 grouped by RADIL-low versus RADIL-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RADIL→partner) and Y-score (partner→RADIL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DKKL1 →	+0.538	+3.643	<.001	.006	3	2
CNS	OR1C1 →	+0.024	+3.700	.001	.003	3	2
LARGE_INTESTINE	SSMEM1 →	+0.014	+1.766	.004	.003	3	2
LUNG_NSCLC_LUAD	ABHD16B →	+0.601	+3.307	.001	.008	3	2
SKIN	RBMY1F →	+0.037	+3.700	.001	.009	3	2
SOFT_TISSUE	CASP14 →	+0.020	+4.459	.009	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 555 associations by consensus.

DKKL1 by RADIL expression — BLOOD_Lymphoma

Explore this box plot interactively →