RAD9B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAD9B mutation is significantly associated with the RNA expression of many other genes, with 1,061 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAD9B-associated genes across cancer lineages are LINC01047, HSPA6, and LINC02353. Each is linked with RAD9B in more than 2 cancer types. Because this analysis shows association rather than direction, both RAD9B-to-partner and partner-to-RAD9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01047 grouped by RAD9B-low versus RAD9B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD9B→partner) and Y-score (partner→RAD9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECLINC01047 →+0.101+1.967<.001<.00133
UCECHSPA6 →+0.797+3.008.007<.00132
SKCMLINC02353 →+0.070+3.300<.001.00732
BLCAMIR4654 →+0.489+4.444<.001.00632
UCECATP6V1G1P3 →+0.100+2.368<.001.00132
COADMIR3135A →+1.057+4.602<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,061 associations by consensus.

LINC01047 by RAD9B expression — UCEC

Box plot of LINC01047 in RAD9B-low vs RAD9B-high samples in UCEC.

Explore this box plot interactively →

Exploration