RAD9B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RAD9B mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RAD9B-associated genes across cancer lineages are TMEM196, GSG1L2, and OR4A47. Each is linked with RAD9B in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD9B-to-partner and partner-to-RAD9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM196 grouped by RAD9B-low versus RAD9B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD9B→partner) and Y-score (partner→RAD9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaTMEM196 →+0.045+4.874<.001.00231
BLOOD_LeukemiaGSG1L2 →+0.043+4.969<.001.00331
BLOOD_LeukemiaOR4A47 →+0.016+4.539<.001.00731
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TMEM196 by RAD9B expression — BLOOD_Leukemia

Box plot of TMEM196 in RAD9B-low vs RAD9B-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration