RAD9A

Across TCGA patient cohorts, RAD9A protein abundance is significantly associated with the RNA expression of many other genes, with 7,015 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RAD9A-associated genes across cancer lineages are POLE2, PPP1CA, and RMI2. Each is linked with RAD9A in more than 4 cancer types. Because this analysis shows association rather than direction, both RAD9A-to-partner and partner-to-RAD9A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAD9A versus POLE2 in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD9A→partner) and Y-score (partner→RAD9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	POLE2 →	+0.877	+0.330	.001	<.001	3	5
BRCA	PPP1CA →	+0.622	+0.351	<.001	<.001	3	5
BRCA	RMI2 →	+0.667	+0.242	<.001	<.001	3	5
HNSC	ASF1B →	+0.980	+0.253	.003	.008	2	5
HNSC	PPP6R3 →	+0.982	+0.312	.001	.008	3	4
LSCC	HELLS →	+0.794	+0.367	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,015 associations by consensus.

RAD9A vs POLE2 — HNSC

Explore this scatter interactively →