RAD9A

Across TCGA patient cohorts, RAD9A mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAD9A-associated genes across cancer lineages are Mre11, PKC-a, and Rb_pS807_S811. Each is linked with RAD9A in more than 1 cancer types. Because this analysis shows association rather than direction, both RAD9A-to-partner and partner-to-RAD9A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mre11 grouped by RAD9A-low versus RAD9A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAD9A→partner) and Y-score (partner→RAD9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Mre11 →	-0.103	-2.321	.016	.035	3	1
UCEC	PKC-a →	+0.400	+2.321	.049	.035	3	1
UCEC	Rb_pS807_S811 →	+0.447	+2.321	.028	.035	3	1
UCEC	Annexin-1 →	+0.548	+2.321	.038	.035	3	1
UCEC	Caspase-7-cleavedD198 →	+0.802	+3.019	.007	.019	3	1
UCEC	Caspase-8 →	-0.286	-3.459	.023	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Mre11 by RAD9A expression — UCEC

Explore this box plot interactively →